Lupus occurs more often in women of childbearing age, but is also diagnosed in men, children, and youths. It is more common in women of color – African American women, Latinas, Asians, Native Americans, Alaska Natives, Native Hawaiians, and other Pacific Islander.
Lupus can be fatal. About 10%-15% of lupus patients will die due to complications of the disease.
Lupus is expensive. Annual direct care costs for lupus patients averaged over $12,000 in 2008, according to one study (Arthritis Rheum. 2008 Dec 15; 59(12): 1788–1795), while productivity loss in working-age patients was estimated at over $8,000.
Questions remain regarding lupus. What causes lupus? Genes play a role, but so do environmental triggers and hormones. What can be done to stave off lupus nephritis, a common and potentially deadly comorbidity? What are potential targets for investigational therapeutics? What can patients do to mitigate against lupus symptoms and thrive despite their chronic disease?